Mississippi Pot Roast is a rich, savory, and tender slow-cooked beef dish with a perfect balance of buttery, tangy, and mildly spicy flavors. This simple, five-ingredient recipe transforms a chuck roast into a melt-in-your-mouth meal, making it a family favorite. It’s an easy, hands-off slow cooker recipe that requires minimal prep but delivers maximum flavor. Serve it over mashed potatoes, rice, or with crusty bread to soak up the delicious gravy!
For a thicker gravy, remove 1 cup of the liquid, mix with 1 tbsp cornstarch, and return it to the slow cooker to thicken.
Milder Version: Reduce the number of pepperoncini peppers or omit the juice.
Spicier Version: Add red pepper flakes or more pepperoncini juice.
Storage: Store leftovers in an airtight container in the fridge for up to 4 days or freeze for up to 3 months.
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